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Clinical Trials/EUCTR2017-001341-27-DK
EUCTR2017-001341-27-DK
Active, not recruiting
Phase 1

Empagliflozin in heart failure patients with reduced ejection fraction:A randomized clinical trial (Empire HF)

Morten Schou0 sites190 target enrollmentApril 10, 2017

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
Morten Schou
Enrollment
190
Status
Active, not recruiting
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 10, 2017
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
Morten Schou

Eligibility Criteria

Inclusion Criteria

  • (1\) Optimal Heart Failure Therapy in accordance with European and National Guidelines
  • (3\) LVEF \= 0\.40
  • (4\) eGFR \> 30 ml/min/1\.73 m2
  • (5\) BMI \< 45 kg/m2
  • (6\) NYHA class I\-III
  • (7\) Age \> 18 years
  • (8\) If T2D – optimal treatment in accordance with European and National Guidelines
  • (9\) If T2D – stable doses of antiglycemic treatment for 30 days
  • (10\) If T2D – HbA1C 6\.5\-10 %
  • Are the trial subjects under 18? no

Exclusion Criteria

  • (1\) CRT\-D/\-P implanted \< 90 days
  • (2\) Uncorrected severe valvular disease
  • (3\) Non\-compliance
  • (4\) Use of metalozone
  • (5\) NYHA IV
  • (6\) Age \> 85 years
  • (7\) Dementia
  • (8\) Admission for HF \< 30 days
  • (9\) Admission for hypoglycemia \< 12 month
  • (10\) Known sustained VT

Outcomes

Primary Outcomes

Not specified

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