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临床试验/NCT03314610
NCT03314610已完成不适用

Effect of Need to Void on Parkinsonian Gait

Pierre and Marie Curie University1 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2017年10月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
11
试验地点
1
主要终点
Gait Speed

研究概览

简要总结

This study evaluates the effect of the need to void on parkinsonian gait

详细描述

Parkinsonian syndromes are common causes of gait disorders, associated with hypometria, bradykinesia or rigidity. If motor disorders are the most visible part, lower urinary tract dysfunction is one of the most prevalent dysautonomic disorder (27-80%), especially over active bladder syndrome (OAB). If it seems evident that gait and urinary disorders are linked, because of similar anatomic pathways and control processes, no studies have investigated their association in extrapyramidal patients.

The aim of this study is to assess the effect of the need to void on the walking speed in this particular population.

This prospective study inclues all parkinsonian syndromes who had a follow-up for OAB. They must have a security delay over five minutes, no severe cognitive, motor or psychiatric disorders. We invite them to drink until a need to void (or equivalent). Bladder filling is measured by bladder scan, then they performe gait tests in a specific place, with calm and no passage : Patient can use their habitual walking device. Speed walk asking is comfortable for the two test. Three ten-meter tests, one double-task ten-meter test, one timed-up-and-go test, one timed raise of the floor (GMT). We repeat the same tests after voiding or self-catheterization. Toilets are just next to the hall where they realize the tests. A clinical examination assesses urinary dysfunction (USP, IPSS), motor score (UPDRS-III, Hoehn and Yahr scale, daily equivalent of levodopa), history of falls and comorbidities.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 99 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Parkinsonian syndromes
  • •Follow in neurourology for Lower urinary tract symptoms
  • •Able to walk 50 meters without human assistance
  • •able to hold voiding for more than 3 minutes

排除标准

  • •Actual urinary tract infection
  • •Montreal cognitive assessment < 20/30
  • •Acute psychiatric or neurologic disorders who can interfer with walking tests

结局指标

主要结局

Gait Speed

时间窗: [Time Frame: 1 Day: at strong desire to void and just after void]

Gait speed calculated from 10 meter walk test. Time is recorded by a manual chronometer. 3 records are done, mean time is calculated.

次要结局

  • Time for Timed up and Go([Time Frame: 1 Day: at strong desire to void and just after void])
  • Variation of gait speed([Time Frame: 1 Day: at strong desire to void and just after void])
  • Time for GMT([Time Frame: 1 Day: at strong desire to void and just after void])

研究者

发起方
Pierre and Marie Curie University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Gérard Amarenco

Head of Neuro-Urology Department, Tenon Hospital

Pierre and Marie Curie University

研究点 (1)

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Effect of Need to Void on Parkinsonian Gait | 临床试验