Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)
Recruiting
- Conditions
- Index of Microvascular ResistanceAngina Patients With Non-obstructive Coronary Artery DiseaseCoronary Microvascular Dysfunction
- Registration Number
- NCT06503640
- Lead Sponsor
- China-Japan Friendship Hospital
- Brief Summary
The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80
Exclusion Criteria
- acute myocardial infarction
- significant valvular heart disease
- advanced chronic kidney disease
- patients with significant epicardial coronary artery stenosis (>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
- patients unable to provide written informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MACE in 12 months 12 months major adverse cardiovascular events 12 months, including cardiac death, myocardial infarction, and readmission for angina.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
China-Japan Friendship Hospital
🇨🇳Beijing, Beijing, China