NCT06503640招募中不适用
Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease
China-Japan Friendship Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- MACE in 12 months
研究概览
简要总结
The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80
排除标准
- •acute myocardial infarction
- •significant valvular heart disease
- •advanced chronic kidney disease
- •patients with significant epicardial coronary artery stenosis (>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
- •patients unable to provide written informed consent
结局指标
主要结局
MACE in 12 months
时间窗: 12 months
major adverse cardiovascular events 12 months, including cardiac death, myocardial infarction, and readmission for angina.
次要结局
未报告次要终点
研究者
Jingang Zheng
Head of Cardiology Department
China-Japan Friendship Hospital
研究点 (1)
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