Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease

China-Japan Friendship Hospital1 site in 1 country100 target enrollmentJuly 1, 2023

ConditionsAngina Patients With Non-obstructive Coronary Artery Disease Coronary Microvascular Dysfunction Index of Microvascular Resistance

Overview

Phase: N/A
Intervention: Not specified
Conditions: Angina Patients With Non-obstructive Coronary Artery Disease
Sponsor: China-Japan Friendship Hospital
Enrollment: 100
Locations: 1
Primary Endpoint: MACE in 12 months
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80.

Registry

clinicaltrials.gov

Start Date

July 1, 2023

End Date

December 31, 2025

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

China-Japan Friendship Hospital

Responsible Party

Principal Investigator

Jingang Zheng

Head of Cardiology Department

China-Japan Friendship Hospital

Eligibility Criteria

Inclusion Criteria

•presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80

Exclusion Criteria

•acute myocardial infarction
•significant valvular heart disease
•advanced chronic kidney disease
•patients with significant epicardial coronary artery stenosis (\>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
•patients unable to provide written informed consent