Circulating microRNAs in cardiovascular disease
Recruiting
- Conditions
- I25Chronic ischaemic heart disease
- Registration Number
- DRKS00000207
- Lead Sponsor
- Institut für kardiovaskuläre Regeneration Zentrum für Molekulare Medizin der J.W. Goethe Universität Frankfurt / Germany
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
Patients with documented stable or unstable coronary artery disease (Acute coronary syndromes). Written informed consent and willigness to give a sample of 20ml venous blood.
Exclusion Criteria
-active Infection
-pregnancy or lactation
-chronic inflammatory disease (i.E. M. Crohn, Rheumatoid Arthritis)
-HIV Infection oder active Hepatitis
-Tumor disease without documented complete remission within the last 5 years
-Stroke within the last 3 month
-mental retardation
-any condition, which excludes a adequate investigation of study data
-participation at an other clinical study within the last 30 days
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evels of circulating serum levels of micro RNA in patients with coronary artery disease.<br>1. Measurement in serum samples<br>2. Correlation with classical risk factors<br>3. Association with systemic endothelial function<br>4. Prognostic impact of micro RNA in patients with CAD
- Secondary Outcome Measures
Name Time Method