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Clinical Trials/DRKS00013659
DRKS00013659
Completed
N/A

Impact of different breathing patterns on autonomic nervous system function in patients with right-ventricular or left-ventricular dysfunction or with normal cardiac function

Klinik für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster0 sites65 target enrollmentMarch 15, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
I50.1
Sponsor
Klinik für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster
Enrollment
65
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 15, 2018
End Date
September 1, 2018
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Klinik für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster

Eligibility Criteria

Inclusion Criteria

  • a. Age \> 18 years (no age limit) (Group 1, 2 and 3\)
  • b. able to consent (Group 1, 2 and 3\)
  • c. Diagnosis of Nizza class I pumonary arterial Hypertension \-PAH\- and heart failure with reduced ejection fraction \-HFrEF\- according to the most recent Guidelines of the European Society of Cardiology (ESC); \>12 weeks since the diagnosis of HFrEF / PAH has been made; no hospitalisation for HF in the last 4 weeks; optimal medical therapy in accordance with the most recent Guidelines of the European Society of Cardiology (ESC) with no change in medication in the last 4 weeks and combination therapy for both PAH and HFrEF \-where there was no treatment with combination therapy in PAH patients or with beta blockers or ACE Inhibitors/ARBs in HFrEF, then the reason must be documented)
  • d. healthy controls (matched for age and gender) with normal findings on echocardiogram, electrocardiogram and normal levels of natriuretic peptide hormone (Group 3\)

Exclusion Criteria

  • \- other severe internistic pre\-existing conditions, especially insulin\-dependent diabetes or severe renal impairment
  • \- severe neurological pre\-existing conditions such as stroke, especially brainstem infarction
  • \- intake of opioids
  • \- psychiatric pre\-existing conditions

Outcomes

Primary Outcomes

Not specified

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