DRKS00013659已完成未知
Impact of different breathing patterns on autonomic nervous system function in patients with right-ventricular or left-ventricular dysfunction or with normal cardiac function
Klinik für Schlafmedizin und neuromuskuläre Erkrankungen Universitätsklinikum Münster0 个研究点目标入组 65 人开始时间: 2018年3月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 65
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •a. Age > 18 years (no age limit) (Group 1, 2 and 3)
- •b. able to consent (Group 1, 2 and 3)
- •c. Diagnosis of Nizza class I pumonary arterial Hypertension -PAH- and heart failure with reduced ejection fraction -HFrEF- according to the most recent Guidelines of the European Society of Cardiology (ESC); >12 weeks since the diagnosis of HFrEF / PAH has been made; no hospitalisation for HF in the last 4 weeks; optimal medical therapy in accordance with the most recent Guidelines of the European Society of Cardiology (ESC) with no change in medication in the last 4 weeks and combination therapy for both PAH and HFrEF -where there was no treatment with combination therapy in PAH patients or with beta blockers or ACE Inhibitors/ARBs in HFrEF, then the reason must be documented)
- •d. healthy controls (matched for age and gender) with normal findings on echocardiogram, electrocardiogram and normal levels of natriuretic peptide hormone (Group 3)
排除标准
- •- other severe internistic pre-existing conditions, especially insulin-dependent diabetes or severe renal impairment
- •- severe neurological pre-existing conditions such as stroke, especially brainstem infarction
- •- intake of opioids
- •- psychiatric pre-existing conditions
研究者
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