Relevance of Reversible Causes During OHCA (Rebecca Study)

Not Applicable

Recruiting

• Conditions: Out-Of-Hospital Cardiac Arrest; Cardiopulmonary Arrest
• Interventions: Diagnostic Test: Checklist for evaluation of reversible causes

• Registration Number: NCT05784480
• Lead Sponsor: Medical University of Vienna

Brief Summary

Management of the reversible causes in cardiac arrest is fundamental for successful treatment of out-of-hospital cardiac arrests. Point-of-care diagnostics as prehospital emergency ultrasound, blood gas analysis and toxicological screening support the diagnostic process of evaluating potential reversible causes. Digital tools provide support of a structured approach. This study aims to evaluate the frequency of reversible causes during OHCA as well as specific interventions due to these findings. Furthermore, CPR performance (hands-off, ROSC, 30-day mortality) and cognitive load of the prehospital emergency physician will be investigated. In total 100 patients with OHCA will be included in this study. Identification of reversible causes will be performed upon a structured protocol using an interactive checklist. Cognitive load of emergency physician as well as CPR parameter (frequency of reversible causes, hands-off, ROSC, 30-day mortality) will be analysed.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-01-06
• Study First Submitted QC: 2023-03-13
• Study First Posted: 2023-03-27
• Study Start: 2023-04-01
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-23
• Last Update Posted: 2023-07-25
• Primary Completion: 2024-04-01
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients with prehospital cardiac arrest, where POCUS, blood gas analysis as well as screening for intoxication can integrated in ALS rhythm without delay of life-saving treatment or transportation will be included.

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Exclusion Criteria

• Patients will be excluded under the age of 18, or if POCUS, blood gas analysis will lead to a delay of live-saving treatment or transportation. Furthermore, pregnant patients will be excluded.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Evaluation of reversible causes using digital checklist and diagnostic support	Checklist for evaluation of reversible causes	-

Primary Outcome Measures

Name	Time	Method
Frequency of reversible causes in OHCA and alterations of treatment	up to 30 days	The primary outcome of this study evaluates the frequency of reversible causes during OHCA.

Secondary Outcome Measures

Name	Time	Method
Frequency of ROSC	up to 30 days	Any prehospital ROSC/sustained ROSC/in-hospital ROSC
Hands-off time	During study completion, up to 120 min	Hands-off time during process of identification of reversible causes
30-day mortality	up to 30 days	rate of mortality within 30 days in case of hospital admission
Cognitive load	1 year (evaluation in documentation phase after CPR)	NASA Task Load Index evaluated by the prehospital emergency physician after rescue mission

Trial Locations

Locations (2)

Anesthesiology and Intensive Care Medicine Department - Medical University of Vienna; 🇦🇹 Vienna, Austria

Department of Anesthesia, General Intensive Care and Pain Management,Medical University of Vienna; 🇦🇹 Vienna, Austria