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临床试验/NL-OMON31595
NL-OMON31595尚未招募3 期

Innovative approaches for cocaine pharmacotherapy using fMRI and SPECT: The case of rimonabant - CoDoRi

Academisch Medisch Centrum0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症

试验速览

阶段
3 期
状态
尚未招募
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • Male, aged 18-60 years;
  • 2) Current DSM-IV diagnosis of cocaine dependence, but recently detoxified and abstinent.
  • 3) Able to provide written informed consent and to comply with all study procedures.

排除标准

  • Exclusion Criteria:
  • 1) Currently dependent on any substance other than cocaine or nicotine;
  • 2) Severe neurological or psychiatric disorders (e.g., depression, psychosis, bipolar illness, dementia, or any diseases that require psychotropic medications);
  • 3) Serious medical illnesses
  • 4) Known hypersensitivity or allergy to rimonabant, or receiving chronic therapy with medication that could interact adversely with one of the medications under study, within 30 days prior to randomization;
  • 5) Drugs known to influence binding to DA2 receptors, including neuroleptics, and methylphenidate
  • 6) Received a drug with known potential for toxicity to a major organ system within the month prior to entering treatment
  • 7) Clinically significant abnormal laboratory values;
  • 8) Any disease of the gastrointestinal system, liver, or kidneys which could result in altered metabolism or excretion of the study medication

研究者

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