Multicentric retrospective prognostic evaluation of tumor volumes and their alteration in the curative-intended radiotherapy of the locally advanced NSCLC

• Conditions: C34; Malignant neoplasm of bronchus and lung

• Registration Number: DRKS00011342
• Lead Sponsor: Klinik für Strahlentherapie und Radioonkologie Halle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11-24
• Study Completion: 2018-07-01
• Results First Posted: 2021-01-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 346

Inclusion Criteria

• histologically confirmed NSCLC (Adeno / PLECA) stage UICC III A or B
• Age> = 18 years
• complete curative-intended radiotherapy (± chemotherapy), normofraction (achieved total dose =60 Gy) or hypofraction (=50 Gy)

Exclusion Criteria

•Stereotactic radiotherapy
•Second malignancy <5 years before diagnosis of NSCLC
•Pleural effusion, extensive atelectasis
•Neoadjuvant chemotherapy before RT

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gross tumor volume (GTV basal, before radiotherapy)

Secondary Outcome Measures

Name	Time	Method
Overall Survival