Benefits of Exercise in Alzheimer's Disease

Not Applicable

• Conditions: Alzheimer's Disease
• Interventions: Other: Personalized Exercise Regimen

• Registration Number: NCT01935024
• Lead Sponsor: University Health Network, Toronto

Brief Summary

Exercise has been shown to be beneficial for the brain. The investigators would like to test this specifically for those diagnosed with Alzheimer's disease. This study will involve 30 randomized patients to take part in the out-patient exercise program and 30 patients to continue with their regular activities over a 6-month period. Once that period is over, half of the 30 patients who participated in the outpatient exercise program will continue in the program and the other half will be randomized to independently continue to exercise. The investigators hypothesize that exercising will benefit the patient by slowing the dementia process, improving behavioral symptoms, and decreasing volume loss of certain brain regions. Each person will perform personalized exercise regimens, MR imaging and neuropsychological tests will be used to measure the benefits of exercise. Ultimately, the hope is that the results of this study could be used to facilitate exercise programs for patients. Enrollment is completely voluntary and all personal data obtained will remain confidential.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-08-01
• Study First Submitted: 2013-08-23
• Study First Submitted QC: 2013-08-29
• Study First Posted: 2013-09-04
• Status Verified: 2019-09
• Last Update Submitted: 2019-09-24
• Last Update Posted: 2019-09-25
• Primary Completion: 2020-04
• Study Completion: 2020-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Personalized Exercise Regimen	Personalized Exercise Regimen	-

Primary Outcome Measures

Name	Time	Method
Neuropsychological Test Battery	Throughout first 6 months of patient participation	The test battery selected comprises of standardized, validated tests focusing on domains including: attention \& concentration, executive functioning, learning and memory, visuospatial, language and semantic memory, pre-morbid intellectual functioning, and speed of processing.

Trial Locations

Locations (1)

Toronto Western Hospital, WW5-449; 🇨🇦 Toronto, Ontario, Canada