The effect of saffron and vitamin E co-supplementation on glycemic control, hormonal, oxidative stress and disease symptom in women with polycystic ovary syndrome

Iran University of Medical Sciences0 个研究点目标入组 66 人开始时间: 待定最近更新: 2024年5月27日

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•Women express their satisfaction by completing a written form to participate in the study.
•2- Diagnosis of polycystic ovary syndrome based on the diagnosis of a gynecologist and having PCOS diagnostic criteria according to the guidelines of the American Association for Reproduction (Rotterdam criteria, 2003 which required at least 2 of the following 3 criteria: 1) oligo and/or Absence of ovulation 2) Clinical or biochemical signs of hyperandrogenism and 3) morphology of polycystic ovary shown in ultrasound examination).
•Women should be between the ages of 18 and 45
•People's BMI should be in the range of 25 to 35.

•A history of chronic diseases including diabetes, liver disease, thyroid, cardiovascular and kidney diseases, and endometriosis.
•Having other disorders that resemble PCOS, including hyperprolactinemia, late-onset congenital adrenal hyperplasia, androgen-secreting tumors, and Cushing's syndrome.
•Following a special diet and exercise
•Use of insulin and insulin sensitizers and other glucose-lowering drugs, contraceptives, weight loss agents and anti-inflammatory drugs.
•Smoking and alcohol consumption in less than 1 month
•Using any food supplements and antioxidants in the last 1 month
•Pregnancy and breastfeeding

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