Treatment Choices for Improving Adherence and Outcome
- Conditions
- Major Depression
- Registration Number
- NCT00194948
- Lead Sponsor
- Weill Medical College of Cornell University
- Brief Summary
This study will determine the effectiveness of offering primary care patients their preferred treatment versus one that is less desirable in improving treatment adherence and outcome.
- Detailed Description
This study investigates whether offering primary care patients treatment that is congruent with their preferred first choice improves adherence and outcomes, in comparison to offering treatment that is not congruent with their preferred first choice. All subjects are offered a treatment with demonstrated efficacy, namely either the antidepressant medication escitalopram or Interpersonal Psychotherapy for 5 months. We hypothesize that patients who receive congruent treatment will be more likely to initiate treatment, adhere to treatment, and achieve depression remission.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- age 21-99
- English-speaking
- DSM-IV criteria for major depression
- unable to give informed consent
- MMSE<24
- DSM-IV diagnosis of bipolar disorder, psychotic disorder, current alcohol or substance abuse
- active suicide ideation
- aphasia
- acute or severe medical illness
- currently receiving either antidepressant medication or psychotherapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method treatment initiation treatment adherence
- Secondary Outcome Measures
Name Time Method depressive symptomatology
Trial Locations
- Locations (2)
Weill Medical College of Cornell University
🇺🇸White Plains, New York, United States
Cornell Internal Medicine Associates
🇺🇸New York, New York, United States