A Pilot Study to Assess the Suitability of DCE-MRI for Detection of Vascular Changes After Vaginal Brachytherapy

Abramson Cancer Center at Penn Medicine1 site in 1 country16 target enrollmentOctober 2013

ConditionsCarcinoma of the Cervix, Carcinoma or Carcinosarcoma of the Uterus

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Carcinoma of the Cervix, Carcinoma or Carcinosarcoma of the Uterus
Sponsor: Abramson Cancer Center at Penn Medicine
Enrollment: 16
Locations: 1
Primary Endpoint: Number of Participants With Adverse Events
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a pilot study of DCE MR imaging to detect vascular changes in the vagina during and after radiotherapy n patients receiving adjuvant brachytherapyfor cervical or endometrial cancer.

Registry

clinicaltrials.gov

Start Date

October 2013

End Date

December 8, 2016

Last Updated

6 years ago

Study Type

Interventional

Study Design

Single Group

Sex

Female

Investigators

Sponsor

Abramson Cancer Center at Penn Medicine

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Must be 18 years of age.
•Must have histologically confirmed carcinoma of the cervix, carcinoma or carcinosarcoma of the uterus.
•Subjects are receiving intracavitary brachytherapy.
•ECOG performance status of 0-
•Creatinine clearance 30.

Exclusion Criteria

•Subjects with an inability to tolerate MR imaging (i.e. claustrphobia)
•Study subjects who have contraindication to MRI scanning such as but not limited to subjects with pacemakers, metal fragments in the eye or certain metallic implants.
•Patients who do not speak or read English.