Suitability of DCE-MRI for Detection of Vascular Changes After VBT
Not Applicable
Completed
- Conditions
- Carcinoma of the Cervix, Carcinoma or Carcinosarcoma of the Uterus
- Interventions
- Radiation: Radiotherapy
- Registration Number
- NCT01991808
- Lead Sponsor
- Abramson Cancer Center at Penn Medicine
- Brief Summary
This is a pilot study of DCE MR imaging to detect vascular changes in the vagina during and after radiotherapy n patients receiving adjuvant brachytherapyfor cervical or endometrial cancer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 16
Inclusion Criteria
- Must be 18 years of age.
- Must have histologically confirmed carcinoma of the cervix, carcinoma or carcinosarcoma of the uterus.
- Subjects are receiving intracavitary brachytherapy.
- ECOG performance status of 0-2.
- Creatinine clearance 30.
Exclusion Criteria
- Subjects with an inability to tolerate MR imaging (i.e. claustrphobia)
- Study subjects who have contraindication to MRI scanning such as but not limited to subjects with pacemakers, metal fragments in the eye or certain metallic implants.
- Patients who do not speak or read English.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description DCE-MRI Radiotherapy -
- Primary Outcome Measures
Name Time Method Number of Participants With Adverse Events 2 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Abramson Cancer Center of the University of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States