Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation
Completed
- Conditions
- Amyloidosis
- Registration Number
- NCT01606280
- Lead Sponsor
- Mayo Clinic
- Brief Summary
This study examines the value of stem cell transplantation in managing light chain amyloidisis.
- Detailed Description
1. How does age at diagnosis affect prognosis in primary amyloidosis?
2. How do lab values at diagnosis such as Creatinine, AST/ALT, total serum protein, serum gamma globulin/immunoglobulin levels affect prognosis in primary amyloidosis?
3. How does degree of organ involvement/number of organs involved affect prognosis in primary amyloidosis?
4. How does initial treatment affect prognosis in primary amyloidosis?
4. How do the specifics the stem cell transplant protocol affect prognosis in primary amyloidosis?
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- Eligible for Stem cell transplantation less than age 75
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Exclusion Criteria
- Creatinine > 3.0
- BNP > 10000
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival up to 8 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mayo Clinic
🇺🇸Rochester, Minnesota, United States