Stenting of venous sinus stenosis for medically refractory idiopathic intracranial hypertension: a cohort study

CHU de Québec0 个研究点目标入组 33 人开始时间: 2015年8月13日最近更新: 2021年1月5日

适应症

试验速览

2018 adverse event report in https://pubmed.ncbi.nlm.nih.gov/28992723/ (added 17/12/2020)

•1. Patients aged 18 and over with diagnosis of IIH according to Friedman diagnostic criteria for whom standard medical treatment has failed (defined as persistent headaches or visual symptoms or papilloedema in spite of 3 months treatment with Diamox or intolerance of side effect of the medication)
•2.Venous imaging (CT, MR or standard venography) showing bilateral transverse sinus stenoses or unilateral transverse sinus stenosis with contralateral transverse sinus atresia. At least one of the stenosis must cause >50% reduction of the sinus lumen.
•3. Pressure gradient across the stenosis >8 mmHg
•4. Signed informed consent obtained from the patient

•1. Allergic reaction to iodine contrast despite premedication
•2. Contraindication to general anaesthesia
•3. Contraindication to aspirin, Clopidogrel (Plavix®) or anticoagulants
•4. Patient with medical history of intracranial venous thrombosis (which do not correspond to idiopathic intracranial hypertension and increase risk of venous stent thrombosis)
•5. Pregnant women

发起方

CHU de Québec