A single-center non-blinded randomized controlled trial on the effect of ovarian hyperstimulation on endometrial receptivity
- Conditions
- subfertility10013356
- Registration Number
- NL-OMON38364
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 193
All couples that present to one of the participating centers for their first IVF/ICSI treatment.
1.Women younger than 18 and older than 38year
2. Couples undergoing a PGD cycle.
3. Couples for which IVF/ICSI is used to prevent the transmission of HIV.
4. Couples undergoing a modified natural cycle.
5. Couples undergoing IVF/ICSI with surgically retrieved spermatozoa.
6. Women with borderline or invasive ovarian cancer.
7. Women with contraindications for IVF/ICSI treatment such as cardiovascular-pulmonary
disease, severe diabetes, bleeding disorders, immunodeficiency and morbid obesity
8. Women with premature ovarian failure.
9. Women with severe psychopathology, severe anxiety and inability to cope with treatment.
10. Not able or willing to provide informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Ongoing pregnancy defined by the presence of a viable intra-uterine pregnancy<br /><br>at 12 weeks of gestation.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes are embryo quality, implantation rate, biochemical<br /><br>pregnancy, clinical pregnancy, multiple pregnancies, live birth, time to<br /><br>pregnancy, health of babies born and costs. </p><br>