Early Detection of the Cerebral Palsy in Moderate and Late Preterms Through the General Movements
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Preterm
- Sponsor
- University of Castilla-La Mancha
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- gestation weeks
- Last Updated
- 6 years ago
Overview
Brief Summary
To analyze the relationship between the early diagnosis of cerebral palsy with the risk factors of this pathology in moderate and late premature infants
Detailed Description
Analyze a sample of moderate and late premature infants using general movements and verify which of them would have an early diagnosis of cerebral palsy and relate it to their risk factors for this pathology.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects who were born between the week 32 + 0 days and the week 36 + 6 days and who are admitted to the Hospital Nuestra Señora del Prado de Talavera de la Reina or the Hospital Virgen de la Salud de Toledo.
Exclusion Criteria
- •Any type of pre and perinatal diagnostic neurological involvement.
- •Any type of pathology associated with prematurity.
- •Children who have prescribed any of the following medications (10):
- •Barbiturates
- •Antiepileptic
- •Indomethacin
- •Dexamethasone
Outcomes
Primary Outcomes
gestation weeks
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
Premature birth week
weight
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
measurement, World Health Organization percentile
size
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
measurement, World Health Organization percentile
Magnetic resonance imaging rating scale
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
Outcome about Neuroimaging in preterms
cranial perimeter
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
measurement about head, World Health Organization percentile
Apgar
Time Frame: at birth of each preterm
Outcome about Apgar Test
general movements outcome
Time Frame: From date of Recruiting until the discharging of neonatal intensive care unit, assessed up to 40 weeks
Outcome about General Movements Assessment. Three outcomes about movement of preterm. Normal, Poor Repertoire and Cramped Synchronized
PERI outcome
Time Frame: through study completion, an average of 18 months
Outcome about Perinatal Risk Scale Scale. Minimum score: 0. Maximum score: 51