An in vitro investigation of coagulation effects of exogenous sugammadex using thromboelastography in orthopaedic surgical patients . - An in vitro investigation of coagulation effects of sugammadex using thromboelastography

Increased sugammadex concentrations were significantly associated with reduced coagulation, as evidenced by the increases in reaction time (r), coagulation time, and time to maximum rate of thrombus generation (TMRTG), and the decreases in the angle, maximum amplitude, and maximum rate of thrombus generation. Compared with the control, the median percentage change (interquartile range) in the TEG values of the samples with the highest exogenous sugammadex concentration was the greatest for r, 53% (26%, 67.3%), and TMRTG, 48% (26%, 59%).