se of novel lung injury markers to predict graft dysfunction after lung transplantatio
Completed
- Conditions
- 10024967chronic bronchitisChronic obstructive pulmonary disease
- Registration Number
- NL-OMON34782
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 38
Inclusion Criteria
Age ><= 18 years
First lung transplantation
Informed consent
Exclusion Criteria
Hyperacute rejection
Venous anastomotic obstruction
Cardiogenic pulmonary edema
Pneumonia (both viral and bacterial pneumonias will be considered)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary endpoint is primary graft dysfunction in the first 72 hours as<br /><br>defined by a classification system from the international society for heart and<br /><br>lung transplantation.</p><br>
- Secondary Outcome Measures
Name Time Method <p>1. Assessment of biomarkers, measured during and post operation (in the<br /><br>recipient), that correlates with the graft function after lung transplantation.<br /><br>2. Assessment of biomarkers, measured during and post operation (in the<br /><br>recipient), that quantifies primary graft dysfunction.</p><br>