Hypothalamic dysfunction and sleep.

• Conditions: pituitary tumors and non-functional pituitary tumors; 10021112

• Registration Number: NL-OMON32008
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

informed consent
tendency to judge
in patients treated for a non-functioning pituitary adenoma:
-representative ITT
-six months of adequate substitution of pituitary hormones

Exclusion Criteria

pregnancy
diagnosed sleepdisorder

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Sleep analysis by polysomnography<br /><br>2. 24 hour bloodpressure and heartbeat.<br /><br>3. 24 hour temperature regulation<br /><br>4. 24 hour rhythm of leptine and melatonine<br /><br>5. fasting lipids and post-prandial lipids.<br /><br>6. quality of life questionnaires<br /><br>7. sleep diary and sleepquestionnaires<br /><br>8. sleepregistration by actigraphy<br /><br>9. ambulant polysomnography<br /><br>10.virgilancy test</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>