Vertigo Symptoms, Balance and Vestibular Function in Patients With Vestibular Schwannoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Vestibular Schwannoma
- Sponsor
- Haukeland University Hospital
- Enrollment
- 155
- Locations
- 1
- Primary Endpoint
- Dizziness Handicap Inventory (DHI)
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
Previous studies have shown that vertigo is the symptoms that mostly affect quality of life in patients with vestibular schwannoma. There is still limited knowledge as to why some patients with this disorder develop vertigo, while others with the same diagnosis do not. The purpose of this study is to measure symptom-related quality of life and to relate this to objective disease characteristics at baseline.
Detailed Description
This is a longitudinal observational study with data collected at baseline and after treatment. Variables collected at baseline include age, sex, tumor size, location, type (cystic/solid), tumor side, symptom variables including Dizziness Handicap Inventory, Vertigo Symptom Scale Short Form, Haukeland Dizziness Questionnaire, Visual analog scale, Hospital Anxiety and Depression Scale, RAND-12, dynamic posturography, video-based head impulse test, bithermal caloric tests, ocular and cervical vestibular evoked myogenic potentials. Follow-up data after 1 year are the same patient-reported outcomes as at baseline.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients living i Norway referred to Haukeland University Hospital due to newly diagnosed, untreated vestibular schwannoma
Exclusion Criteria
- •Inability to undergo test protocol due to physical or language barriers
Outcomes
Primary Outcomes
Dizziness Handicap Inventory (DHI)
Time Frame: Baseline and 1-year follow-up
25-item symptom score 0 - 100 points on dizziness handicap severity
Secondary Outcomes
- Vertigo Symptom Scale Short Form(Baseline and 1-year follow-up)
- Haukeland Dizziness Questionnaire (HDQ-10)(Baseline and 1-year follow-up)
- Hospital Anxiety and Depression Scale (HADS)(Baseline and 1-year follow-up)
- RAND-12(Baseline and 1-year follow-up)
- Vertigo Visual Analog Scale(Baseline and 1-year follow-up)