Age-related changes in fatigue, fatigability and dexterity in persons with MS

Recruiting

• Conditions: multiple sclerosis; 10012303

• Registration Number: NL-OMON49981
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 140

Inclusion Criteria

• Diagnosed with Multiple sclerosis
• Being able to hold the force transducer and Pegboard pins

Exclusion Criteria

• Neurological or muscle disorders other than MS
• Other conditions affecting fatigue
• Depressive symptoms

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in persons with MS and in controls over three time points (present<br /><br>time, after 5 and after 10 years) in:<br /><br>a) the number of pins placed in a Purdue pegboard task;<br /><br>b) maximal handgrip and index finger abduction force and<br /><br>c) the decline in force over a 2-minute sustained maximal contraction.<br /><br>d) the number of correct digits in the symbol digit modality test.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>