A Prospective, Randomised, Double-blind, Placebo Controlled Study to assess the Role of Aloe Vera with or without Glucosamine & Chondroitin in Patients with Symptomatic Osteoarthritis of Knees

Not Applicable

Completed

• Conditions: Musculoskeletal Diseases: Osteoarthritis of the knee; Musculoskeletal Diseases; Osteoarthritis of the knee

• Registration Number: ISRCTN01562001
• Lead Sponsor: Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09-28
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Age between 18 - 80 years
2. Symptoms of episodic or continuous pain in the affected knee joint for 6 weeks
3. Diagnosis of OA of Knee made according to ACR criteria (knee pain and radiographic osteophytes and at least any one of the following 3 items: a) Age > 50 years b) Morning Stiffness < 30 minutes in duration c) Crepitus on motion

Exclusion Criteria

1. Any contra indication to Aloe Vera /Glucosamine/Chondroitin
2. Current Use or use within 3 months of screening of aloe vera/Glucosamine/Chondroitin
3. Current or Previous history of oral steroid or injection in the study joint within 3 months
4.Current or previous history of Intra articular Synvisc or Hyalgan therapy
5. Previous history of NSAID topical application within the last 3 months
6. Any previous history of Knee surgery including Menisectomy / patellectomy etc
7. Presence of Inflammatory Arthritis
8. Presence of significant hip disease on the side of symptomatic knee

Study & Design

• Study Type: Interventional
• Study Design: Not specified