A comparative study of the effects of oral magnesium versus placebo in migraine prophylaxis in pregnancy period
Phase 3
- Conditions
- Migraine without aura (common migraine)Migraine with aura (classical migraine)Condition 1: Common Migraine. Condition 2: Classical Migraine.
- Registration Number
- IRCT2016062128559N1
- Lead Sponsor
- Vice-chancellor for research, Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 64
Inclusion Criteria
Diagnosis of migraine according to definition of International Headache Society by a neurologist; at least one year has passed form the time of migraine onset; moderate to severe headache; more than 2 headache attacks per month.
Exclusion criteria: Having tension headaches or other non-migraine headaches; overuse of analgesic medications (more than 15 days a month); use of any migraine prophylactic drugs; history of previous or recently infection; history of chronic diseases (diabetes, hypertension, cardiac, vascular, renal and hepatic); use of mineral supplements; substance and alcohol abuse.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of headache. Timepoint: In each migraine attack. Method of measurement: Patient will record the headache severity in daily notes as VAS, MIDAS,HITS-6& physician registers them every 4 weeks.;Duration of migraine attack. Timepoint: In each migraine attack. Method of measurement: Patient records the hours of headache in each attack , physician registers them every 4 weeks.;Headache frequency. Timepoint: In each migraine attack. Method of measurement: According to patient records.;Analgesic use. Timepoint: Every 4 week. Method of measurement: According to patient records.
- Secondary Outcome Measures
Name Time Method Clinical side effects. Timepoint: Every 4 weeks. Method of measurement: According to patients notes.