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Clinical Trials/NCT00519922
NCT00519922
Completed
N/A

Efficacy of Kinesthesia, Balance and Agility Exercise Training as Treatment of Knee Osteoarthritis: A Pilot Study

The Arthritis Research Institute of America1 site in 1 country30 target enrollmentJanuary 2008

Overview

Phase
N/A
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
The Arthritis Research Institute of America
Enrollment
30
Locations
1
Primary Endpoint
WOMAC Osteoarthritis Scale; Function subscale change pre to post intervention - KBA vs. standard strength training
Status
Completed
Last Updated
17 years ago

Overview

Brief Summary

This pilot study will test the testing and exercise training protocols for a larger study that is in the desing phase and may be modified based on the findings of this study. Two exercise groups will be compared; one is a stadard treatment group using leg strength exercises that are commonly employed in therapy clinics. The other group will do balance and agility type exercises, but no specific strength exercises. These "KBA" exercises are increasingly common in therapy clinics, but very little research has been conducted on their effectiveness in treating knee osteoarthritis symptoms. Participants in this study will complete three short paper and pencil tests at the beginning and end of the study (8 weeks of exercise) as well as a leg strength test, a leg endurance test, two short walking tests, and a stair climb/descend test. One of the paper and pencil tests will be taken every two weeks in an effort to see how quickly changes to symptoms might occur. The exercise programs will be conducted 3 afternoons per week (Mon-Wed-Fri) and will be lead by an ACSM certified instructor.

Detailed Description

Radiographic knee OA is present in an estimated 37% of Americans over the age of 60, representing more than 13 million people. Current medical, non-surgical knee OA treatments focus primarily on symptomatic relief and have met with limited, temporary success. Various therapeutic exercise prescriptions have been used to help ameliorate knee OA symptoms and improve function. Leg strength training is most commonly used. However, recent evidence suggests that shorter programs of kinesthesia, balance and agility (KBA) techniques may result in more rapid symptom relief and functional improvements in comparison to traditional therapeutic exercise. These early benefits could potentially lead to greater long term exercise adherence. In a case study of an elderly female patient with dynamic knee instability related to OA, physical therapists reported success with a combination of KBA training and traditional therapeutic exercise. These findings need to be verified in a controlled clinical trial. This pilot study will help determine the proper testing and exercise training methods for a larger clinical trial, and will indicate if KBA training done without concurrent strength training is a viable intervention. Research Hypothesis: Among men and women age 50 and over with Kellgren and Lawrence (1957) Grade 2 or higher symptomatic tibiofemoral OA in one or both knees, an 8-week, 3-day per week kinesthesia, balance \& agility (KBA) exercise program - designed to increase dynamic neuromuscular knee stability - safely and effectively changes physical function more effectively than standard leg strength training

Registry
clinicaltrials.gov
Start Date
January 2008
End Date
July 2008
Last Updated
17 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
The Arthritis Research Institute of America

Eligibility Criteria

Inclusion Criteria

  • Aged 50 years or over of either gender
  • Radiographic tibiofemoral OA grade 2 or higher, unilateral or bilateral
  • Demonstrated knee OA related dysfunction per WOMAC score
  • Not engaged in a regular exercise program for minimum of 6 months

Exclusion Criteria

  • Inability to obtain physician release for exercise
  • High risk health status:
  • e.g., uncontrolled medical conditions such as hypertension, diabetes, heart disease, pulmonary disease, high cholesterol, anginal type pain, dizziness or syncope, orthopnea or paroxysmal nocturnal dyspnea, ankle edema, heart palpitations or tachycardia, intermittent claudication, known heart murmur, unusual fatigue or shortness of breath with usual activities.
  • Unresolved balance disorder
  • Unresolved neurological disorder
  • History of knee surgery or major knee trauma injury
  • Hip or ankle instability, excessive weakness, surgery or major trauma injury
  • Intra-articular joint injection within 4 weeks of the study

Outcomes

Primary Outcomes

WOMAC Osteoarthritis Scale; Function subscale change pre to post intervention - KBA vs. standard strength training

Time Frame: 8 weeks

Secondary Outcomes

  • WOMAC subscale change in Pain and in Stiffness pre to post intervention(8 weeks)
  • Walking speed change in a timed Get Up & Go Test pre to post intervention(8 weeks)
  • Stair climbing and descending speed change pre to post intervention(8 weeks)
  • Gait quality measures with the GAITRite walking mat and EMG, pre to post intervention(8 weeks)
  • Spontaneous engagement in physical activity - change pre to post intervention as measured by the Human Activity Profile(8 weeks)
  • Efficacy for exercise change pre to post intervention as measured by the Self-Efficacy for Exercise scale.(8 weeks)

Study Sites (1)

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