Comparing effect of magnesium sulfate and normal saline on intraoperative hemodynamic of patients undergoing cerebral ?aneurism surgery and rate of postoperative cerebral vasospasm?

Vice Chancellor for Research, Mashhad University of Medical Sciences0 个研究点目标入组 46 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•The major inclusion criteria?:?
•candidate for brain aneurysm surgery after 3 days of aneurysm bleeding;?
•American Society of Anesthesiologists (ASA) class I and II.?
•The major exclusion criteria:?
•pathology of cardiovascular system; heart failure [Ejection fraction (EF) less than ??40%].
•Previous history of hypertension; Liver or kidney diseases (impaired Liver function ?test (FT) and Glomerular filtration rate (GFR) less than 50 ml/min); Motor, ?neurological, and muscle disorders, coagulopathy [Prothrombin time (PT) more than ??16, International Normalized Ratio (INR) more than 1.5; Partial thromboplastin ?time (PTT) more than 35]; Hypomagnesaemia, More than 60 years of age;? History of allergy to any of the used medications in the experiment,?
•? Overweight [Body mass index (BMI) more than 30]; Previous use of calcium channel ?blockers; Atrioventricular block.?

发起方

Vice Chancellor for Research, Mashhad University of Medical Sciences