Post -Extubation Respiratory Failure

Not Applicable

Completed

• Conditions: Respiratory Insufficiency

• Registration Number: NCT04441736
• Lead Sponsor: Cairo University

Brief Summary

comparing high flow nasal cannula , conventional oxygen tharapy and non invasive ventilation post-extubation period for patients mechanically ventilated due to respiratory failure regarding re-intubation rate, ICU outcome \& 28 days mortality

Detailed Description

patients with respiratory failure either type I or type II planned for extubation will be divided into 3 groups post extubation :

Group I: will receive high flow nasal cannula giving oxygen 60 litres / minute flow group II: will receive nasal cannula up to 10 litres / minute group III: will receive non invasive ventilation

Data of the patients will be collected for 28 days post-extubation and analysed

Study Timeline

• Study Start: 2019-02-20
• Primary Completion: 2020-05-30
• Study Completion: 2020-05-31
• Study First Submitted: 2020-06-10
• Study First Submitted QC: 2020-06-19
• Study First Posted: 2020-06-22
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-30
• Last Update Posted: 2024-05-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• respiratory failure type I and Type II

Exclusion Criteria

• Mechanical ventilation due to other cause such as disturbed conscious level or respiratory muscle weakness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Number of participants with post extubation respiratory failure	7 days	Number of participants with post extubation hypoxemia with or without hypercapnea

Secondary Outcome Measures

Name	Time	Method
Rate of ICU stay and mortality	28 days	Duration of ICU stay and incidence of mortality

Trial Locations

Locations (1)

Faculty of Medicine; 🇪🇬 Giza, Egypt