A phase I study of SPM-011 and BNCT30 in patients with recurrent malignant glioma
Phase 1
- Conditions
- Recurrent malignant glioma
- Registration Number
- JPRN-jRCT2051210053
- Lead Sponsor
- Miyatake Shin-ichi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 9
Inclusion Criteria
1. Karnofsky performance status >= 60
2. Patients with recurrent malignant glioma confirmed by imaging or histological diagnosis with previous radiotherapy to the target lesion.
3. Patients who have received 50 Gy to 65 Gy of prior radiation therapy to the target lesion and more than 180 days have passed since the last irradiation.
Exclusion Criteria
1. Patients with active multiple primary cancers
2. Patients with meningeal dissemination or two or more discontinuous tumor lesions
3. Patients who are using steroids other than for the treatment of cerebral edema or who have complications requiring systemic administration of steroids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method