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A Study to Test How Well Different Doses of BI 3810477 Are Tolerated by Healthy Men

Phase 1
Active, not recruiting
Conditions
Healthy
Interventions
Drug: Placebo
Registration Number
NCT06631430
Lead Sponsor
Boehringer Ingelheim
Brief Summary

The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 3810477 in healthy male subjects.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Male
Target Recruitment
24
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Part A: BI 3810477 formulation A dose group 1BI 3810477single dose group 1
Part A: BI 3810477 formulation A dose group 2BI 3810477single dose group 2
Part A: BI 3810477 formulation A dose group 3BI 3810477single dose group 3
Part A: BI 3810477 formulation A dose group 4BI 3810477single dose group 4
Part A: BI 3810477 formulation A dose group 5BI 3810477single dose group 5
Part A: BI 3810477 formulation A dose group 6BI 3810477single dose group 6
Part A: BI 3810477 formulation A dose group 7BI 3810477single dose group 7
Part B: BI 3810477 formulation B dose group 1BI 3810477single dose group 1
Part B: BI 3810477 formulation B dose group 2BI 3810477single dose group 2
Part B: BI 3810477 formulation B dose group 3BI 3810477single dose group 3
Part A and Part B_PlaceboPlacebosingle dose of placebo
Primary Outcome Measures
NameTimeMethod
Occurrence of any treatment-emergent adverse event assessed as drug-related by the investigatorUp to Day 85
Secondary Outcome Measures
NameTimeMethod
Area under the concentration-time curve of the analyte in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)Up to Day 85
Maximum measured concentration of the analyte in plasma (Cmax)Up to Day 85

Trial Locations

Locations (1)

SGS Life Science Services - Clinical Research

🇧🇪

Edegem, Belgium

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