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Clinical Trials/CTRI/2023/10/058621
CTRI/2023/10/058621
Not Yet Recruiting
Phase 2

Accelerated Hypofractionated Palliative Radiotherapy Vs Standard Hypofractionated Palliative Radiotherapy With Concurrent Chemotherapy In Locally Advanced Head And Neck Carcinoma: A Randomised Controlled Study - nil

AIIMS, New Delhi0 sites0 target enrollmentTBD
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Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
AIIMS, New Delhi
Status
Not Yet Recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
AIIMS, New Delhi

Eligibility Criteria

Inclusion Criteria

  • •Treatment naive, Histo\-pathologically proven Squamous Cell Carcinoma of head and neck region excluding nasopharyngeal, para\-nasal sinus and salivary gland primary
  • •\-Defined as incurable or palliative intent by Head and Neck multidisciplinary team (MDT)
  • •\-Adequate organ functions and bone marrow reserve
  • •\-Eastern Co\-operative Oncology Group Performance Score (ECOG PS)\- (0\-3\)
  • •\-Age: 18\- 70 years
  • •\-Negative viral serology markers (HIV, HBsAg, HCV)
  • •\-Giving written Informed consent

Exclusion Criteria

  • •\-Nasopharyngeal, para\-nasal sinus or salivary gland primary
  • •\-Recurrent disease
  • •\-Metastatic disease
  • •\-Patients who have previously received oncologic treatment with surgery, radiotherapy or chemotherapy
  • •\-Pregnant patients
  • •\-Synchronous malignancy or any other malignancy with in last 5 years
  • •\-Known uncontrolled medical comorbidities which could impact QOL

Outcomes

Primary Outcomes

Not specified

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