Study on evaluation of perfusion index as a tool to assess the analgesic efficacy of dexmedetomidine during laparoscopic cholecystectomy under general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Primary outcome - incidence and severity of intra-op pain stimulus assessed using perfusion index tool
研究概览
简要总结
Quantifying nociception under anaesthesia is difficult and therefore reaction to nociception is used for monitoring through increased sympathetic activity or the corresponding decreased sympathetic stimulation
In any way surgical procedures as far as an anaesthetist is concerned in providing pain free journey is most important. So to identify nociceptive condition as fast as possible via an effective simple reliable tool is important. The usual parameters we use for pain assessment is heart rate, blood pressure variation and in this study we are assessing whether perfusion index can assess the nociceptive changes in surgery in an effective and reliable way.
In this study we mainly aim at comparing the parameters used for assessing pain like heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure along with variations of perfusion index in patients receiving dexmedetomidine infusion intra operatively and patients receiving conventional anaesthesia for laparoscopic cholecystectomy procedures.
After meeting inclusion and exclusion criteria a total number of 60 patients will be recruited for this longitudinal study in a consecutive sampling manner.
Primary objective of study is to compare the variation in perfusion index in response to pain stimulus and variability of perfusion index in subsequent pain stimulus after intravenous administration of dexmedetomidine during laparoscopic cholecystectomy surgeries under General anaesthesia and to compare the perfusion index with hemodynamic parameters such as heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure with or without dexmedetomidine
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Physical state ASA 1-2 Age group 18 years to 70 years Patients undergoing elective laparoscopic cholecystectomy surgeries under General anaesthesia.
排除标准
- •Patients not willing to participate in this study History of allergy to the drugs in the study Patients with neurological or psychiatric illness,chronic pain disorder.
结局指标
主要结局
Primary outcome - incidence and severity of intra-op pain stimulus assessed using perfusion index tool
时间窗: Before induction,after induction,after intubation,1,2,3,2,4,6,8,10,15,20,25,30 minutes
次要结局
- Comparison of perfusion index with hemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure(Before induction, after induction, after intubation,1,2,3,2,4,6,8,10,15,20,25,30 minutes)