IRCT2013121215765N1CompletedPhase 2
Metformin and placebo effects on TSH and thyroid volume in patients with pre-diabetes
Isfahan Endocrine and Metabolism Research Center0 sites76 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Enrollment
- 76
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 65 years (—)
- Sex
- All
Inclusion Criteria
- •Inclusion criteria :patients with pre-diabetes [Impaired fasting plasma glucose (100 to 125 mg/dl) or impaired glucose tolerance (IGT) (2-h PG OGTT values of 140–199 mg/dL and having 18 to 65 years old] were initially included.
- •Exclusion criteria:
- •Those patients with thyroid malignancy or any other malignancy; previous-thyroxin suppression therapy at any time; obesity due to endocrine disease; Pregnancy and lactation; renal failure or liver failure; neurological or psychological disorders (depression, epilepsy, schizophrenia); heart failure; hypothyroidism or hyperthyroidism; smoking and finally iodinated contrast material exposure in the previous 6 months ago all were excluded from the study.
Exclusion Criteria
- Not provided
Investigators
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