Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal Subjects
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Corneal endothelium cell number
研究概览
简要总结
The purpose of this study is to compare corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with special reference to glycemic status.
详细描述
Diabetes might influence the health of the corneal endothelium. Older studies have presented different results and the glycemic status of the patients have not been reported. In this study we examine the corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with modern specular microscopy. Each patient and control is examined once ("entry to study").
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Type II diabetes (diagnose confirmed by general practitioner)
- •Controls with no diabetes (confirmed by blood testing).
排除标准
- •Uveitis (current or previous)
- •Corneal scaring
- •Previous eye surgery
结局指标
主要结局
Corneal endothelium cell number
时间窗: 1 year
The study is a cross-sectional study. We compare a cohort of patients with DM to a cohort with no DM. We examine each patient and control once. We call time of appointment or examination for "at entry to study".
次要结局
- Corneal endothelium morphology(1 year)