A Comparative clinical trial to evaluate the efficacy of Pippalyadikshar Gutika and Khadiradi Vati in management of Galagraha with reference to acute pharyngitis.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Sane Guruji Arogya Kendra
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Kanthashopa, Kanthakandu, Aaraktata will be decreased, subject will get relief from
Study Overview
Brief Summary
There are various Galaroga’s explained by different Acharya’s among which is Galagraha is explained by Acharya Charaka.According to Acharya Charaka, kapha Dosha get aggravated due to different Hetusevana and it gets localised inside Gala region and produces local oedema.Acharya Kashyapa has given the symptoms of Galagraha like Jwara, Aruchi, Mukhastrava, and difficulty in breathing.Galaroga’s means Gala;throat region (pharynx and larynx).i.e. Galaroga’s occur at respiratory pathway therefore there is risk of obstruction in respiration. Hence they should be treated as soon they occur. As pharynx is common passage in both process of respiration and digestion and that’s why diseases of this throat region should be treated immediately to avoid further complication like pneumonia, sinusitis etc), Pharyngitis (ICD Code 10-J02.9) is the inflammation of mucus membrane of oropharynx. It occurs due to varied etiological factors like viral, bacterial, fungal, and allergic factors such as mold, pollen, smoke, air, food, animal hairs, others. Discomfort in throat, some malaise and low-grade fever are seen. Pharynx in this region shows erythema.According to modern point of view antibiotics, analgesics, warm saline gargles are used for treating pharyngitis. But recurrent use of antibiotics, analgesics may cause resistance to medicines, hence the purpose of this study is to find permanent solution by Ayurvedic formulations.Vati means medicine in the tablet form, made up of combinations of various fine Ayurvedic Churna according to their properties.Vati Dharana means Vati kept in mouth for Dharana Karma, Vati is kept in mouth then it will mix with the saliva and ultimately it will help in reducing local symptoms like congestion, pain quickly.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- None
Eligibility Criteria
- Ages
- 19.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients of age group 19 to 60 years, irrespective of their gender, occupation.
- •All patients having signs and symptoms in Gala region as a) Kanthashopha (Oedema in Oro-pharyngeal region) b) Kanthakandu(ItchinginOro-pharyngealregion) c) Aaraktata (Posterior pharyngeal wall congestion) religion,
- •All patients having body temperature ranging from 98.6 °F to 100 °F.
Exclusion Criteria
- •Patients having moderate to high grade fever, having body temperature above 100 °F
- •Patients having chronic conditions in pharynx like carcinoma in the pharynx / throat region/ oral cavity.
- •Patients having systemic illnesses like HTN,DM,HIV, Tuberculosis.
Outcomes
Primary Outcomes
Kanthashopa, Kanthakandu, Aaraktata will be decreased, subject will get relief from
Time Frame: Follow Up will be taken on 3rd and 7th day .Symptoms will be noted before and after treatment.
Galagraha.
Time Frame: Follow Up will be taken on 3rd and 7th day .Symptoms will be noted before and after treatment.
Secondary Outcomes
- Subject will get relief from Jwara (Low Grade Fever).(18 Months)
Investigators
Dr Pallavi Gangadhar Nimalwar
Mams Sumatibhai Shah Ayurved Mahavidyalaya,Hadapsar,Pune
