Open prospective single arm real practice trial of long term doxycycline in asthma

Institute of Pulmocare Research0 个研究点目标入组 30 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•a)Willing to participate in the trial.
•b)History of SOB with wheeze with variability (seasonal, diurnal, others) with h/o spontaneous recovery (wellbeing) or relief from oral or inhaled bronchodialators with or without family history of diagnosed or suggestive asthma and / or allergic rhinitis with documentation of airflow limitation with or without reversibility.
•c)Thus both certain and possible cases of chronic asthmatics will be incorporated.

•i)Age 13 yrs and75yrs
•ii)Unwillingly for informed written consent
•iii)H/o doxycycline intolerance
•iv)Very sick patient unable for follow up.
•v)Significant Co-morbidity â?? that can affect the spirometric performance or the synptomatology.
•vi)FEV160% of predicted value
•vii)Clinically obvious anemia and HB% if measured 7.0 gm%
•viii)Pregnancy and lactation
•ix)Exacerbation in last 6 weeks.
•x)No other obvious lung disease as assessed by the physician

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