A study to determine whether doxycycline, an antibiotic, can help patients with bronchial asthma.
- Conditions
- Health Condition 1: null- Asthma
- Registration Number
- CTRI/2012/01/002328
- Lead Sponsor
- Institute of Pulmocare Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
a)Willing to participate in the trial.
b)History of SOB with wheeze with variability (seasonal, diurnal, others) with h/o spontaneous recovery (wellbeing) or relief from oral or inhaled bronchodialators with or without family history of diagnosed or suggestive asthma and / or allergic rhinitis with documentation of airflow limitation with or without reversibility.
c)Thus both certain and possible cases of chronic asthmatics will be incorporated.
i)Age 13 yrs and75yrs
ii)Unwillingly for informed written consent
iii)H/o doxycycline intolerance
iv)Very sick patient unable for follow up.
v)Significant Co-morbidity â?? that can affect the spirometric performance or the synptomatology.
vi)FEV160% of predicted value
vii)Clinically obvious anemia and HB% if measured 7.0 gm%
viii)Pregnancy and lactation
ix)Exacerbation in last 6 weeks.
x)No other obvious lung disease as assessed by the physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change in both pre and post FEVITimepoint: preferably at least 6 months of continuation of doxycycline therapy
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI