Evaluation on the acute cutaneous tolerance of Hydrogel sheet, Aloe vera coated hydrogel sheet, Silver nanoparticles coated hydrogel sheet and CARISS Facial cream
- Conditions
- Healthy Thai subjects
- Registration Number
- TCTR20190612001
- Lead Sponsor
- Thailand institute od Nuclear Technology (Public Organization) (Head Office)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 33
1. Healthy female and male volunteers of all skin types with an age range 20-60 years old
2. Free of wound, scar or any skin disease on the test area
3.Willing to participate in the study after being informed on objective, methodology, possible risk and expecting outcome of the study
4. Be able to read, write and communicate in Thai
5. Willing to sign consent of the volunteer
1. History of hypersensitive skin
2. History of eczema or psoriasis within 6 months before the study
3. History of medical treatment with steroids, antibiotic, NSAIDs, anti-histamine within 3 days before the study
4. History of using topical medicine on the test area within 3 weeks before the study
5. Having any disease on the test area that required regular use of any topical medicine
6. History of major operation within 1 year
7. History of skin cancer within 1 year
8. Pregnancy or lactation
9. Heavy smoker or regular drink
10. History of addiction to any narcotic substances
11. History of all allergenic reaction to Aloe vera or Silver nitrate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin irritation test 0, 0.5, 1, 24h 24 hours patch test
- Secondary Outcome Measures
Name Time Method /A N/A N/A