临床试验/NCT00345202

NCT00345202已完成4 期

Short Term Effects of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects.

Regional Hospital Holstebro2 个研究点分布在 1 个国家目标入组 20 人开始时间: 2004年9月1日最近更新: 2008年5月15日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方
入组人数: 20
试验地点: 2
主要终点: GFR

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

We wanted to test the shortterm effects of HMG-CoA reductase inhibition (atorvastatin) on renal hemodynamics, renal tubular function and vasoactive hormones on healthy subjects.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
盲法: Double

入排标准

年龄范围: 20 Years 至 50 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•Both men and women
•Age: Between 20-50

排除标准

•Cl. signs or history of disease of heart, lungs, kidneys or endocrine organs.
•Abnormal lab. tests( haemoglobin, pl. sodium, pl. potassium, pl.creatinine, pl.bilirubin, pl.ALAT, pl. cholesterol, blood glucose)
•Albuminuria or glucosuria
•Art. hypertension
•Alcohol abuse
•Med. treatment, except oral contraceptives
•Pregnancy or breast feeding
•Blood donation less than 1 month before study

结局指标

主要结局

GFR

RPF

FEna

FELi

CLna

CLli

次要结局

未报告次要终点

研究者

发起方

Regional Hospital Holstebro

申办方类型

Other

研究点 (2)

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