Etiology, Epidemiology, Antimicrobial sensitivity and Outcome of community acquired pneumonia at Max Super Speciality Hospital, Saket, New Delhi
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- it will be measured at the end of study in term of Organism responsible for community acquired pneumonia, epidemiology and their antimicrobial sensitivity.
研究概览
简要总结
Aim & Objective: Toevaluate the Etiology, Epidemiology, Antimicrobial sensitivity and Outcome ofCommunity-Acquired Pneumonia (CAP).
Outcome: it will bemeasured at the end of study in term of Organism responsible for communityacquired pneumonia, epidemiology and their antimicrobial sensitivity.
Design: Prospectiveepidemiologic study, to be done at MAX SUPER SPECIALITY HOSPITAL, SAKET, NEWDELHI
MATERIAL AND METHODS:-
All adult more than 18 years ofage, between August, 2012 and July, 2013, who will be treated at Max SuperSpecialty Hospital (A Unit Of Max Healthcare Institute Limited), Saket, NewDelhi with clinical diagnosis of community acquired pneumonia will be studiedprospectively. It will include the patients that come in as out patientsdepartment or ER or inpatients department and occasionally patient admitted inother department with other presumptive illness and in whom a diagnosis of CAPmade during the 24 hr of hospitalization
Patient demographic features willbe recorded according to study proforma. A detailed clinical history will betaken. History for co morbid illness and habits like smoking and alcoholism arewill be taken. Co morbid illnesses were defined as the presence of coexistingcardiac failure, ischemic heart disease, chronic lung disease (COPD), chronicliver disease (cirrhosis of liver), chronic kidney disease (diabeticnephropathy) and diabetes mellitus. A detailed clinical examination will becarried out including general physical examination, vital signs, andrespiratory system examination, mainly for signs of consolidation and othersystemic examination for the co morbid illness. Routine investigations likehemoglobin, total leucocytes count, differential count, ESR, random bloodsugar, renal profile, liver function tests, spo2 and paired blood culture willbe recorded. Radiological evaluation inform of chest x ray will be done. Sputumwill be collected for gram stain and culture and sensitivity, other investigationwill be recorded if they are done, are CRP, Procalcitonin and CECT chest.
Outcome of CAP will be measuredin term of in clinical improvement OR lab parameter improvement OR radiologicalimprovement.
A) Clinicalimprovement includes-Body temperature, Pulse rate, Systolic BP, Respiratoryrate and Spo2.
B) Labimprovement includes-TLC,[CRP and Procalcitonin- if done].
C) Radiologicalimprovement by comparing day 1st chest x- ray and last chest x- ray availableat the time of discharge in IPD patients and follow up chest x- ray in OPDpatients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •(a) Age >18 years, (b) Clinical symptoms like:- [5]
- •Fever (temperature >37.8°C)
- •Production of purulent sputum
- •Leucocytosis (WBC count > 10,000/cu.mm) (c) Radiological evidence of pneumonia without any clinical evidence of pneumonia will also be included.
排除标准
- •(a) Hospital acquired pneumonia that is patient hospitalized in the previous 14 days.
- •(b) Known history of HIV-positive status.
- •(c) Known history of tuberculosis.
- •(d) Known history of lung malignancies.
结局指标
主要结局
it will be measured at the end of study in term of Organism responsible for community acquired pneumonia, epidemiology and their antimicrobial sensitivity.
时间窗: Approx 1 year
次要结局
- Not Applicable(Not Applicable)
