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Clinical Trials/NCT02287090
NCT02287090
Completed
Not Applicable

Comparative Effectiveness of Operative Versus Non-Operative Treatments for Rotator Cuff Tears

Vanderbilt University Medical Center4 sites in 1 country400 target enrollmentMarch 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rotator Cuff Tear
Sponsor
Vanderbilt University Medical Center
Enrollment
400
Locations
4
Primary Endpoint
Pain/Function (as measured by the SPADI outcome score)
Status
Completed
Last Updated
last year

Overview

Brief Summary

Rotator cuff tears are one of the most common causes of shoulder pain. Evidence-based guidance on optimal diagnostic and treatment strategies for rotator cuff tears is lacking. Our proposed study aims to fill these gaps by identifying the prognostic factors which will predict better outcomes of rotator cuff tears, based on both operative and non-operative treatment. The investigators will also compare outcomes of operative and non-operative treatment of rotator cuff tears and report on the best way to diagnose rotator cuff tears.

Detailed Description

Rotator cuff tears account for over one quarter million surgeries annually. They are a leading cause of shoulder pain and disability. Patients with rotator cuff tears present with shoulder pain and/or limitation in range of motion. Fourteen special physical exam tests have been described for diagnosis of rotator cuff tears. Prior literature describing sensitivity and specificity of these tests in diagnosing cuff tears is limited by retrospective design, small sample sizes, samples restricted to patients undergoing surgery, and failure to differentiate between partial and full thickness tears. As a result, there is little evidence to help clinicians interpret the diagnostic value of the clinical exam. Consequently, clinicians rely heavily on magnetic resonance imaging (MRI) for diagnosing cuff tears, adding considerable expense in the diagnostic process. The treatment options for rotator cuff tears are operative and non-operative. There is currently little consensus on indications and timing of rotator cuff surgery or non-operative treatment. Furthermore, there is lack of evidence-based guidance on factors associated with outcomes of operative versus non-operative treatment for cuff tears. We are enrolling patients in a prospective cohort study to assess comparative-effectiveness of operative versus non-operative treatment of rotator cuff tears and understand prognostic factors for better outcomes after surgery and non-operative treatments.

Registry
clinicaltrials.gov
Start Date
March 2011
End Date
December 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nitin Jain

Associate Professor of Physical Medicine and Rehabilitation and Orthopaedics

Vanderbilt University

Eligibility Criteria

Inclusion Criteria

  • Age 45 or older
  • Symptoms for at least 4 weeks of shoulder pain and/or limitation in range of motion of shoulder

Exclusion Criteria

  • History of humeral fractures
  • Prior surgery on the same shoulder
  • Contraindications to MRI (prior surgical hardware, pacemakers, defibrillators, and claustrophobia)
  • Unable or unwilling to give informed consent
  • Unable or unwilling to be followed up
  • Non-English speaking (as questionnaires have only been validated in English)

Outcomes

Primary Outcomes

Pain/Function (as measured by the SPADI outcome score)

Time Frame: 24 months

Comparing patient pain/function \[as measured by the Shoulder Pain and Disability Index (SPADI) outcome instrument\] between patients undergoing surgery and patients choosing non-operative treatment.

Secondary Outcomes

  • Pain/Function (as measured by the ASES outcome score)(24 months)
  • Pain/Function (as measured by the QuickDash outcome score)(24 months)
  • Effects of rotator cuff tear size on outcomes (as measured by the SPADI outcome instrument).(24 months)
  • Effects of patient age on outcomes (as measured by the SPADI outcome instrument).(24 months)

Study Sites (4)

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