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临床试验/NCT05050435
NCT05050435Unknown不适用

Early Cardiac Extubation After Cardiac Surgery: a Retrospective Single-center Non-inferiority Trial

University of Liege1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2021年8月30日最近更新:
适应症

试验速览

阶段
不适用
入组人数
500
试验地点
1
主要终点
Post-operative complications

研究概览

简要总结

The management of heart valve disease is constantly evolving over time. The minimally invasive approach (mini-thoracotomy and J-hemisternotomy) is one of the major surgical evolutions. It has many advantages including, among others, a reduction of postoperative pain and the preservation of sternal stability This evolution of the surgical technique towards a less invasive approach encouraged the investigators to adapt the anesthetic management accordingly. In particular, immediate postoperative extubation appeared feasible. The investigators would therefore like to test the hypothesis that immediate extuation is non-inferior to delayed extubation with regard to patient safety. The investigators also investigated whether immediate extubation could be beneficiel in terms of vasopressors requirement, risk of early postoperative complications, fluid balance and length of stay in the intesive care unit and in the hopsital.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Minimally invasive valve replacement intervention (thoracotomy or J-hemisternotomy)

排除标准

  • Combined surgery

结局指标

主要结局

Post-operative complications

时间窗: 30 days

Intensive care unit length of stay (days)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jean François Brichant

Head of department

University of Liege

研究点 (1)

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