Plasmin Enzyme-assisted Vitrectomy for Pediatric Patients with Vitreoretinal Diseases in Taiwa

Not Applicable

Completed

• Conditions: the efficacy of plasmin- plasmin; posterior vitreous detachment; vitreous; assisted vitrectomythe safety of plasmin- retina; vitreoretinopathy; assisted vitrectomy; vitrectomy; pediatric

• Registration Number: TCTR20140610001
• Lead Sponsor: Chang Gung Medical Research Project (CMRPG381661)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2013-08-31
• Study Start: 2014-06-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

Patients aged 16 years or younger with vitreoretinopathy associated with abnormal vitreoretinal adhesion were enrolled for the use of plasmin as an adjuvant to vitreoretinal surgery

Exclusion Criteria

Patients with active human immunodeficiency virus hepatitis B virus or hepatitis C were excluded from this trial Eyes with PVD at presentation sign of active infection history of uveitis or glaucoma uncontrolled by ocular hypotensive agents were excluded

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the induction of posterior vitreous detachment during the surgery intraoperative period and postoperative 1 day,1 week, 2 weeks, 1 month, 2 months, 3 months, 6 months percentage of posterior vitreous detachment during surgery

Secondary Outcome Measures

Name	Time	Method
the restoration of retinal anatomy and visual acuity postoperative 1 day, 1 week, 2 weeks, 1 month, 2 months, 3 months, 6 months visual acuity (logMAR unit); fundus photography, optical coherence tomography