The Effect of Caffeine as Endurance Enhancing Drug in the Elderly
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- endurance measured on an ergometer bicycle
研究概览
简要总结
The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.
详细描述
Caffeine ingestion increases the endurance of young people exercising at 60%-85% of their maximal oxygen uptake, and it also seems to improve endurance as measured by repeated sub-maximal isometric contraction and decreases the rate of perceived exertion during exercise. Although caffeine increases endurance in young people, an increase in endurance may be of greater interest in the elderly as the population of older adults with a physically active lifestyle is growing rapidly or for increasing endurance fitness through an exercise or rehabilitation program. Therefore the main hypothesis was that caffeine would improve cycling endurance at 65% of expected maximal heart rate, and the secondary hypotheses were that caffeine would improve postural stability, reaction and movement times, isometric arm flexion endurance, and walking speed, and would reduce the rate of perceived exertion after 5 minutes of cycling in healthy elderly citizens.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 70 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy elderly individuals aged over 70 years
排除标准
- •Dementia or invalidating psychiatric disease
- •General debility, angina, or other diseases that would render participation in the test program impossible
- •Treatment with beta receptor blocking drugs, calcium-channel blocking drugs, digitalis, or nitroglycerine
- •Acute disease and injury
- •Conditions that would contraindicate caffeine ingestion or participation in the test program
- •Treatment with medication that interacts with caffeine
- •Ingestion of caffeine containing drinks and foods 48 hours before each session
结局指标
主要结局
endurance measured on an ergometer bicycle
次要结局
- postural stability
- reactiontime
- isometric endurance (armflexion)
- walking speed
- fatigue
