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Clinical Trials/NCT06497751
NCT06497751
Recruiting
N/A

Pilot Randomized Controlled Trial of Couple-based Intervention on Relationship Satisfaction and Quality of Life in HIV Male Serodiscordant Couples

City University of Hong Kong4 sites in 1 country100 target enrollmentJuly 1, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Quality of Life
Sponsor
City University of Hong Kong
Enrollment
100
Locations
4
Primary Endpoint
Perceived Acceptability, Appropriateness, and Feasibility
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This study aims to provide preliminary evidence of the efficacy of couple-based intervention over usual care in HIV serodiscordant couples in China. The investigators hypothesize that couple-based intervention would be more effective than usual care concerning both partners' quality of life and relationship satisfaction. The investigators also pilot the feasibility, acceptability, and appropriateness of the intervention content and implementation.

HIV serodiscordant couples in the intervention arm will receive three sessions of dyadic intervention. In contrast, couples in the control arm will receive usual care.

Registry
clinicaltrials.gov
Start Date
July 1, 2024
End Date
October 31, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Nancy Xiaonan Yu

Associate Professor

City University of Hong Kong

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Perceived Acceptability, Appropriateness, and Feasibility

Time Frame: One month (immediately after the last session of intervention)

Perceived acceptability, appropriateness, and feasibility will be assessed using the 12-item Implementation Outcome Inventory (Weiner et al., 2017). Only couples in the intervention group will answer this scale. Items are scored on a five-point scale (0-4). The total score for this scale is calculated by summing all items. The score range is 0-48. Higher scores indicate a higher level of acceptability, appropriateness, and feasibility.

Change of Health-related Quality of Life

Time Frame: Baseline, one month (immediately after the last session of intervention), and two month

Health-related quality of life will be measured using the 24-item World Health Organization Quality of Life, which contains four domains (i.e., physical, psychological, social relationships, and environment) (WHO, 1998). Both partners will answer this scale. Items are scored on a five-point scale (0-4). The total score for this scale is calculated by summing the scores for the four domains. The score range is 0-96. Higher scores indicate a higher level of quality of life.

Change of Relationship Satisfaction

Time Frame: Baseline, one month (immediately after the last session of intervention), and two month

Relationship satisfaction will be assessed using the 4-item Couple Satisfaction Index (Funk \&Rogger, 2007). Both partners will answer this scale. Items are scored on a six-point scale (0-5). The total score for this scale is calculated by summing all items. The score range is 0-20. Higher scores indicate a higher level of relationship satisfaction.

Secondary Outcomes

  • Change of Well-being(Baseline, one month (immediately after the last session of intervention), and two month)
  • Percentage of Couples Agreeing to Participate(Baseline)
  • Change of We-disease Appraisal(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Antiretroviral therapy Adherence(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Dyadic Coping(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Depressive Symptoms(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Condom Use with Study Partner(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Active Listening(Baseline, one month (immediately after the last session of intervention), and two month)
  • Change of Self-regulation in Relationship(Baseline, one month (immediately after the last session of intervention), and two month)
  • Percentage of Couples Randomized to the Intervention Arm Completed All Three Sessions(One month (immediately after the last session of intervention))

Study Sites (4)

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