跳至主要内容
临床试验/JPRN-jRCT1050210160
JPRN-jRCT1050210160进行中(未招募)未知

Observational Study of RAS monitoring for RAS/BRAF wild advanced Colorectal Cancer Patients treated with anti EGFR antibody - RAS-trace

Kataoka Kozo0 个研究点目标入组 40 人开始时间: 2022年1月22日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
>= 20age old 至 ot applicable(—)
性别
All

入选标准

  • 1)Histologically proven for colorectal cancer
  • 2)Clinical Stage III/IV colorectal cancer for which more than 12 cycles of chemotherapy including anti-EGFR therapy is planned.
  • 3)measurable lesions according to RECIST ver1.1
  • 4)No previous history of chemotherapy and radiotherapy
  • 5)Aged 20 years old and over
  • 6)ECOG PS0-1
  • 7)Consent for blood exam for ctDNA analy
  • 8)Written informed consent

排除标准

  • 1)Active other malignancies
  • 2)Pregnancy, possible pregnancy or breastfeeding
  • 3)Severe pulmonary fibrosis or emphysema
  • 4)Psychiatric disease
  • 5)Patients requiring systemic steroid medication
  • 6) Grade 2 or greater diarrhea or sensory neuropathy
  • 7)Poorly controlled hypertension
  • 8)History of severe heart disease, heart failure, unstable angina within 6 months or angina attack with 6 months
  • 9) active COVID-19 infection

研究者

发起方
Kataoka Kozo

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