JPRN-jRCT1050210160进行中(未招募)未知
Observational Study of RAS monitoring for RAS/BRAF wild advanced Colorectal Cancer Patients treated with anti EGFR antibody - RAS-trace
Kataoka Kozo0 个研究点目标入组 40 人开始时间: 2022年1月22日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- >= 20age old 至 ot applicable(—)
- 性别
- All
入选标准
- •1)Histologically proven for colorectal cancer
- •2)Clinical Stage III/IV colorectal cancer for which more than 12 cycles of chemotherapy including anti-EGFR therapy is planned.
- •3)measurable lesions according to RECIST ver1.1
- •4)No previous history of chemotherapy and radiotherapy
- •5)Aged 20 years old and over
- •6)ECOG PS0-1
- •7)Consent for blood exam for ctDNA analy
- •8)Written informed consent
排除标准
- •1)Active other malignancies
- •2)Pregnancy, possible pregnancy or breastfeeding
- •3)Severe pulmonary fibrosis or emphysema
- •4)Psychiatric disease
- •5)Patients requiring systemic steroid medication
- •6) Grade 2 or greater diarrhea or sensory neuropathy
- •7)Poorly controlled hypertension
- •8)History of severe heart disease, heart failure, unstable angina within 6 months or angina attack with 6 months
- •9) active COVID-19 infection
研究者
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