NCT01721187已完成不适用
Functional Magnetic Resonance Imaging Study of the Valuation of Food as a Function of Satiety
Duke-NUS Graduate Medical School1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2012年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- fMRI - Willingness to Pay task (BDM auction)
研究概览
简要总结
Using fMRI, this study will explore the neural correlates of satiety when individuals make decisions about food. The investigators will also examine individual differences in satiety effects.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 21 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Chinese ethnicity
- •21 to 45 years old
- •English as first language
- •Right-handed
- •Have normal eyesight, or have long-sightedness or myopia within +8.0 to -8.0 diopters (unless corrected by contact lenses)
- •Weigh less than 100kg with an abdominal circumference of less than 120cm
- •Non-smoker, or only smoke occasionally (less than 5 sticks a week)
- •Consume less than 2 units (200 mg) of caffeine a day
- •Consume less than 21 units of alcohol per week (e.g. 500ml 5% beer = 2.5 units, 250ml 14% wine = 3.5 unit)
- •Habitually sleep before 1am and wake before 9am
排除标准
- •On a restrictive diet (e.g., vegetarian/vegan diet)
- •History of food allergies
- •History of psychiatric or neurological disorders
- •History of chronic medical illness
- •Metal implants in or on the body (e.g. braces, dental retainers, pacemakers)
- •Shift worker
- •Claustrophobic
- •High astigmatism (high = >2.00 diopters)
- •Colour-blind
结局指标
主要结局
fMRI - Willingness to Pay task (BDM auction)
时间窗: Fed and fasted visits (Wks 1 & 2)
A measurement of how much participants are willing to pay for foods and non-foods, as an assay for subjective value of goods.
fMRI - Monetary and Food Incentive Delay task
时间窗: Fed and fasted visits (Wks 1 & 2)
A measurement of neural response to anticipating and receiving money and food rewards.
次要结局
未报告次要终点
研究者
MChee
Professor
Duke-NUS Graduate Medical School
研究点 (1)
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