The Effect of High-Volume Walking With Visual Cues (VC) in Parkinson´s Disease (PD)

Phase 3

Completed

• Conditions: Parkinson´s Disease
• Interventions: Other: Visual Cues; Other: Walking without visual cues

• Registration Number: NCT01391741
• Lead Sponsor: University of Iceland

Brief Summary

People with disease (PD) tend to walk with short steps, decreased velocity, and increased stride time variability. Short steps and increased variability are related to greater fall risk. In addition, concurrent performance of a cognitive task (dual-task (DT)) has marked effects on gait in people with PD which is considered to reflect an impaired automaticity of gait.

Objective: To investigate short and long term effects of high-volume walking with visual spatial cues (VSC) on gait variables, automaticity, and functional mobility, in people with Parkinson´s Disease (PD), compared with walking without VSC.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04
• Primary Completion: 2008-09
• Study Completion: 2008-09
• Status Verified: 2010-03
• Study First Submitted: 2011-07-07
• Study First Submitted QC: 2011-07-11
• Last Update Submitted: 2011-07-11
• Study First Posted: 2011-07-12
• Last Update Posted: 2011-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• a confirmed diagnosis of PD according to the UK Parkinson´s Disease Society Brain Bank Clinical Diagnostic Criteria (18)
• <80 years of age
• community residing
• Hoehn and Yahr (HY) stage 2-3
• Mini Mental State Examination (MMSE) score of >23
• ability to walk without walking aids for a total of 20 minutes over a 30-minute period

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Exclusion Criteria

• major modifications of Parkinson´s medication (Madopar >200 mg/d or >20% increase in Dopamine agonists) 3 weeks prior to baseline assessment
• comorbidities or disabilities, which might influence walking
• a history of brain surgery

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Walking with visual cues	Visual Cues	Walking with visual cues for 30 minutes, 4 times a week for 4 weeks
Walking without visual cues	Walking without visual cues	Walking without visual cues, but verbal encouragement twice a week to take longer steps, for 30 minutes, 4 times a week for 4 weeks.

Primary Outcome Measures

Name	Time	Method
Change in Step Length	Before, after and 3 months after a 4 week training period
Change in Gait Velocity	Before, after and 3 months after a 4 week training period
Change in Stride Time Variability	Before, after and 3 months after a 4 week training period

Secondary Outcome Measures

Name	Time	Method
Change in Timed Up & Go (seconds)	Before, after and 3 months after a 4 week training period

Trial Locations

Locations (1)

Reykjalundur Rehabilitation Center; 🇮🇸 Mosfellsbaer, Iceland