study of effect of local Tranexamic acid in reducing postoperative bleeding on ?coronary artery bypass graft ?

Phase 2

Recruiting

• Conditions: Coronary bypass graft.; Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris; I25.70

• Registration Number: IRCT20141209020258N62
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Patients with elective CABG referrals
ASA Class 2 and 3
Tranexamic acid insensitivity
Surgery performed by a surgeon
Duration of surgery 4 to 6 hours

Exclusion Criteria

Increase the duration of the operation for more than 6 hours
cardiomegaly and CHF
Going on a cardio-pulmonary pump for 2 times during operation
All patients who die during surgery
History of cardiac arrest and CPR before surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bleeding after surgery. Timepoint: after surgery. Method of measurement: score.;Mean number of PACs received during 24 hours after surgery. Timepoint: 24 hours after surgery. Method of measurement: count.;Mean number of unit platelets received within 24 hours after surgery. Timepoint: 24 hours after surgery. Method of measurement: count.;Mean of number of FFP units received within 24 hours of surgery. Timepoint: 24 hours after surgery. Method of measurement: count.;The average number of returns to the operating room to control bleeding within 24 hours of operation. Timepoint: 24 hours after surgery. Method of measurement: count.