Deciphering the evolution of viral pathogens in the context of human immunity
Recruiting
- Conditions
- SARS-CoV-2 infection and immunityInfluenza virus infection and immunityViral respiratory tract infections
- Registration Number
- DRKS00026266
- Lead Sponsor
- niklinik Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Good physical condition (Karnofsky-Index =80%)
Exclusion Criteria
- <8 weeks (men)/<12 Wochen (women) since last blood draw of a volume of =500 ml
- Current or planned participation in an interventional vaccine study during the duration of this study
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immunity against viral respiratory pathogens (longitudinal assessment every four months; serum/plasma antibody and neutralization titer)
- Secondary Outcome Measures
Name Time Method Selection pressure on viral respiratory pathogens (at the end of the study; neutralizing serum/plasma activity against ciruclating viral variants)