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Treatment efficacy of 0.05% cyclosporine eyedrop on ocular surface changes after anti-glaucoma medication in glaucoma patients.

Not Applicable
Recruiting
Conditions
Diseases of the eye and adnexa
Registration Number
KCT0007124
Lead Sponsor
Keimyung University Dongsan Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1) A patient with glaucoma who is 19 years of age or older and has been instilling one or more antiglaucoma eye drops bilaterally for at least one,
2) Based on the Korean dry eye treatment guidelines at the time of first enrolling, and the diagnostic criteria presented by the Dry Eye Workshop in 2007, dry eye syndrome of level 2 or higher
3) Patients who can be followed up for at least 4 months
4) Patients who accurately understands the details of the clinical trial and has written a consent form from a voluntary doctor

Exclusion Criteria

1) Level 1 and 2 mild dry eye syndrome patients
2) Those who have had hypersensitivity reactions to this drug or other drugs, or those with a history of clinically significant hypersensitivity reactions
3) Patients who are pregnant, lactating, or planning to become pregnant
4) Those who participated in other clinical trials within 3 months before the first administration date
5) If there is a history of corneal or glaucoma surgery or intraocular surgery within 6 months of screening
6) Patients who want to wear contact lenses during the clinical trial period
7) Patients with eye diseases that require treatment other than dry eye syndrome and glaucoma
8) Patients received lacrimal punctal surgery (punctal plug and surgical lacrimal closure) within 1 month before instillation

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ocular surface disease index;Tear break up time;Ocular surface score
Secondary Outcome Measures
NameTimeMethod
Best corrected visual acuity;intraocular pressure;tear meniscus height;Matrix metalloproteinase-9;tear osmolality;Schirmer's test;Visual field test
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