Prongs or mask for nasal continuous positive airway pressure (CPAP) in preterm infants

Completed

• Conditions: Respiratory; Respiratory distress of newborn

• Registration Number: ISRCTN43000196
• Lead Sponsor: The National Children's Research Centre (Ireland)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09-02
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Infants born less than or equal to 30 weeks' gestation by best obstetric estimate, either sex
2. Receive nasal CPAP using the Infant Flow Driver or SiPAP machine (Viasys, Yorba Linda CA, USA) in the neonatal intensive care unit

Exclusion Criteria

Infants with congenital anomalies

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intubation and mechanical ventilation less than or equal to 72 hours of starting treatment, indicated by at least two of the five criteria:<br>1. Worsening clinical respiratory distress<br>2. Recurrent apnoeic episodes<br>3. Oxygen requirement greater than 40% to keep oxygen saturations greater than 85% for greater than 30 minutes<br>4. pH less than 7.2 on two blood gases at least 30 minutes apart<br>5. Carbon dioxide (PCO2) greater than 9kPa on two blood gases at least 30 minutes apart